重組細胞
expressed in baculovirus infected Sf9 cells
產品線
PRECISIO® Kinase
化驗
≥70% (SDS-PAGE)
形狀
buffered aqueous glycerol solution
比活性
30-40 nmol/min·mg
分子量
~73 kDa
NCBI登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
mouse ... Epha7(13841)
一般說明
EPHA7 is a member of the ephrin receptor subfamily of protein-tyrosine kinases family that have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2-fibronectin types III repeats. EPHA7 mediated signaling act as a physiologic trigger for apoptosis that can alter brain size and shape by regulating the number of neural progenitors. The high expression of EPHA7 protein plays an important role in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma.
外觀
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
準備報告
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
法律資訊
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Shui-jun Zhang et al.
Zhonghua wai ke za zhi [Chinese journal of surgery], 48(1), 53-56 (2010-03-23)
To investigate the expression and clinical significance of EphA7 protein in primary hepatocellular carcinoma. Immunohistochemistry and Western blot were used to detect the expression of EphA7 protein in 40 cases of primary hepatocellular carcinoma, their corresponding adjacent liver tissues and
Vanessa Depaepe et al.
Nature, 435(7046), 1244-1250 (2005-05-20)
Mechanisms controlling brain size include the regulation of neural progenitor cell proliferation, differentiation, survival and migration. Here we show that ephrin-A/EphA receptor signalling plays a key role in controlling the size of the mouse cerebral cortex by regulating cortical progenitor
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