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Merck

SRP5210

Sigma-Aldrich

FLT4 (800-end), active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

FLT41, LMPH1A, PCL, VEGFR3

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

重組細胞

expressed in baculovirus infected Sf9 cells

產品線

PRECISIO® Kinase

化驗

≥70% (SDS-PAGE)

形狀

buffered aqueous glycerol solution

比活性

57.8-78.2 nmol/min·mg

分子量

~85 kDa

NCBI登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... FLT4(2324)

一般說明

FLT4 or fms-related tyrosine kinase 4 is a tyrosine kinase receptor for vascular endothelial growth factors C and D and highly expressed in lymphangiogenesis and maintenance of the lymphatic endothelium. FLT4 is a marker for lymphatic vessels and some high endothelial venules in human adult tissues and also supported the theory of the venous origin of lymphatic vessels. FLT4 plays an essential role in the development of the embryonic cardiovascular system before the emergence of the lymphatic vessels.

外觀

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

準備報告

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

法律資訊

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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D J Dumont et al.
Science (New York, N.Y.), 282(5390), 946-949 (1998-10-30)
Vascular endothelial growth factor (VEGF) is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGF-C stimulates the growth of lymphatic vessels through its specific lymphatic endothelial receptor VEGFR-3. Here it
A Kaipainen et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(8), 3566-3570 (1995-04-11)
We have recently cloned the human fms-like tyrosine kinase 4 gene FLT4, whose protein product is related to two vascular endothelial growth factor receptors FLT1 and KDR/FLK1. Here the expression of FLT4 has been analyzed by in situ hybridization during

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