生物源
mouse
重組細胞
expressed in E. coli
化驗
≥98% (HPLC)
≥98% (SDS-PAGE)
形狀
lyophilized
效力
10.0-100.0 ng/mL
分子量
10.9 kDa
包裝
pkg of 20 μg
技術
cell culture | mammalian: suitable
雜質
<0.1 EU/μg endotoxin, tested
顏色
off-white to yellow
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
mouse ... CCL27(20301)
一般說明
CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant murine CTACK is a 10.9 kDa protein containing 95 amino acid residues.
生化/生理作用
CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Recombinant murine CTACK is a 10.9 kDa protein containing 95 amino acid residues.
序列
LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN
外觀
Lyophilized with no additives.
重構
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
J Morales et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(25), 14470-14475 (1999-12-10)
In contrast to naive lymphocytes, memory/effector lymphocytes can access nonlymphoid effector sites and display restricted, often tissue-selective, migration behavior. The cutaneous lymphocyte-associated antigen (CLA) defines a subset of circulating memory T cells that selectively localize in cutaneous sites mediated in
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