生物来源
human
重组
expressed in E. coli
方案
≥70% (SDS-PAGE)
表单
frozen liquid
分子量
~61.2 kDa
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
浓度
400 μg/mL
颜色
clear colorless
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... GTF2B(2959)
生化/生理作用
The transcription factor IIB (TFIIB) is an essential factor for transcription by RNA polymerase II. TFIIB has been shown to be required for selective binding of RNA polymerase II, TFIIF and TFIID-DNA complex, and for specifying the start site of transcription. Human TFIIB is a single, 35 kDa polypeptide, homologous to yeast factor, the product of the SUA7 gene.
外形
Clear and colorless frozen liquid solution
制备说明
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
General initiation factors for RNA polymerase II.
R C Conaway et al.
Annual review of biochemistry, 62, 161-190 (1993-01-01)
S Malik et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(21), 9553-9557 (1991-11-01)
Transcription factor TFIIB is a ubiquitous factor required for transcription initiation by RNA polymerase II. Previous studies have suggested that TFIIB serves as a bridge between the "TATA"-binding factor (TFIID) and RNA polymerase II during preinitiation complex assembly and, more
The general transcription factors of RNA polymerase II.
G Orphanides et al.
Genes & development, 10(21), 2657-2683 (1996-11-01)
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