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Merck

SRP0381

Sigma-Aldrich

EZH2/EED/SUZ12/RbAp48/AEBP2 人

recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥90% (SDS-PAGE)

形狀

aqueous solution

分子量

48 kDa (RbBP5)
51 kDa (EED)
53 kDa (AEBP2)
86 kDa (EZH2)
87 kDa (SUZ12)

包裝

pkg of 20 μg

運輸包裝

dry ice

儲存溫度

−70°C

一般說明

Mutant version of EZH2 5 member complex, with a Tyr- to-Ser mutation on amino acids 646 of the EZH2 protein (GenBank Accession No. NM_004456). This mutation is often cited in the scientific literature as Y641S in variant 3 (GenBank Accession No. NM_001203247).

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Ryan D Morin et al.
Nature genetics, 42(2), 181-185 (2010-01-19)
Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL) derive from germinal center B cells. Targeted resequencing studies have revealed mutations in various genes encoding proteins in the NF-kappaB pathway that contribute to the activated B-cell

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