生物源
human
重組細胞
expressed in baculovirus infected Sf9 cells
化驗
≥90% (SDS-PAGE)
形狀
aqueous solution
分子量
48 kDa (RbBP5)
51 kDa (EED)
53 kDa (AEBP2)
86 kDa (EZH2)
87 kDa (SUZ12)
包裝
pkg of 20 μg
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... AEBP2(121536) , EED(8726) , EZH2(2146) , RBBP4(5928) , SUZ12(23512)
一般說明
Mutant version of EZH2 5 member complex, with a Tyr- to-Ser mutation on amino acids 646 of the EZH2 protein (GenBank Accession No. NM_004456). This mutation is often cited in the scientific literature as Y641S in variant 3 (GenBank Accession No. NM_001203247).
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Nature genetics, 42(2), 181-185 (2010-01-19)
Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL) derive from germinal center B cells. Targeted resequencing studies have revealed mutations in various genes encoding proteins in the NF-kappaB pathway that contribute to the activated B-cell
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