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Merck

SRP0321

Sigma-Aldrich

JMJD2D active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)

别名:

KDM4D, lysine (K)-specific demethylase 4D

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥90% (SDS-PAGE)

形狀

aqueous solution

分子量

67 kDa

包裝

pkg of 100 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... KDM4D(55693)

一般說明

Human JMJD2D, also known as KDM4D (GenBank Accession No. NM_018039), amino-acids 2-354 with N-terminal GST tag, MW=67 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

應用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Sook Shin et al.
Biochemical and biophysical research communications, 353(4), 973-977 (2007-01-09)
JMJD2A-D belong to the JmjC domain-containing family of histone demethylases. JMJD2D is the most structurally divergent JMJD2 protein as it lacks the PHD and Tudor domains present in JMJD2A-C. Here, we systematically analyzed the histone demethylase specificity of JMJD2 proteins
Masuko Katoh et al.
International journal of oncology, 24(6), 1623-1628 (2004-05-13)
JMJD1 family genes, including JMJD1 (TSGA), TRIP8, and C5orf7 (5qNCA), encode nuclear proteins with Jumonji C (JmjC), TRI8H1 and TRI8H2 domains. Here, we identified JMJD2 family genes. Human genes corresponding to KIAA0677, KIAA0876, KIAA0780 and FLJ10251 cDNAs were designated JMJD2A

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