跳转至内容
Merck
所有图片(1)

文件

SML3579

Sigma-Aldrich

Pyrimethamine

≥98% (HPLC)

别名:

2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C12H13ClN4
CAS号:
58-14-0
分子量:
248.71
MDL號碼:
MFCD00057350
分類程式碼代碼:
12352116
分類程式碼代碼:
12352200
NACRES:
NA.21

品質等級

100

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear (Wramed)

儲存溫度

2-8°C

InChI

1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

InChI 密鑰

WKSAUQYGYAYLPV-UHFFFAOYSA-N

生化／生理作用

Pyrimethamine is an antiparasitic drug used to treat malaria, toxoplasmosis and cystoisosporiasis. Pyrimethamine is a potent inhibitor of dihydrofolate reductase.

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance
C V Plowe
The Journal of Infectious Diseases, 176, 1590-1596 (1997)
The multifaceted antineoplastic role of pyrimethamine against human malignancies
Shanaya Ramchandani
IUBMB Life, 74, 198-212 (2022)
Lisa N Heppler et al.
The Journal of biological chemistry, 298(2), 101531-101531 (2021-12-27)
Cancer is often characterized by aberrant gene expression patterns caused by the inappropriate activation of transcription factors. Signal transducer and activator of transcription 3 (STAT3) is a key transcriptional regulator of many protumorigenic processes and is persistently activated in many

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门