化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
−20°C
SMILES 字串
ClC1=CC=C([N+]([O-])=O)C=C1C(NC2=C(C=C(OC)C=C3)C3=NC=C2)=O
生化／生理作用
SR16832 is a PPARγ antagonist. It acts as a dual-site covalent inhibitor of PPARγ inhibiting both orthosteric and allosteric cellular activation by the PPARγ agonists.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Richard Brust et al.
ACS chemical biology, 12(4), 969-978 (2017-02-07)
GW9662 and T0070907 are widely used commercially available irreversible antagonists of peroxisome proliferator-activated receptor gamma (PPARγ). These antagonists covalently modify Cys285 located in an orthosteric ligand-binding pocket embedded in the PPARγ ligand-binding domain and are used to block binding of
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