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品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 20 mg/mL, clear
儲存溫度
2-8°C
InChI
1S/C18H21NO4S/c1-18(2,3)10-6-7-11-13(9-10)24-16(14(11)17(21)22)19-15(20)12-5-4-8-23-12/h4-5,8,10H,6-7,9H2,1-3H3,(H,19,20)(H,21,22)
InChI 密鑰
ACLUEOBQFRYTQS-UHFFFAOYSA-N
生化／生理作用
CaCCinh-A01 是一种 TMEM16A（跨膜成员 16A）抑制剂。它还能阻断 anoctamin-1 (ANO1)，降低细胞活力，抑制细胞迁移。
CaCCinh-A01 是一种强效的钙激活氯离子通道 (CaCC) 抑制剂，可完全抑制人支气管和肠细胞中的 CaCC 电流。CaCCinh-A01 不抑制 CFTR。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ca2+-activated Cl? channel currents in mammary secretory cells from lactating mouse.
Kamikawa A, et al.
American Journal of Physiology. Cell Physiology, 311(5), C808-C819 (2016)
Inhibition of calcium-activated chloride channel ANO1 suppresses proliferation and induces apoptosis of epithelium originated cancer cells.
Guan L, et al.
Oncotarget, 7(48), 78619-78619 (2016)
Ana N Gonçalves et al.
Respiratory research, 24(1), 42-42 (2023-02-06)
Clinical and experimental evidence shows lung fluid volume as a modulator of fetal lung growth with important value in treating fetal lung hypoplasia. Thus, understanding the mechanisms underlying these morphological dynamics has been the topic of multiple investigations with, however
Hayley Pearson et al.
Thorax, 76(1), 64-72 (2020-10-29)
Human respiratory syncytial virus (HRSV) is a common cause of respiratory tract infections (RTIs) globally and is one of the most fatal infectious diseases for infants in developing countries. Of those infected, 25%-40% aged ≤1 year develop severe lower RTIs leading to
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