SML0818

A-841720

≥98% (HPLC)

• 别名: 9-(Dimethylamino)-3-(hexahydro-1H-azepin-1-yl)-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one
• 经验公式（希尔记法）: C₁₇H₂₁N₅OS
• CAS号: 869802-58-4
• 分子量: 343.45
• UNSPSC代码: 12352202
• NACRES: NA.77

属性

• 质量水平: 100
• 方案: ≥98% (HPLC)
• 表单: powder
• 颜色: white to beige
• 溶解性: DMSO: 15 mg/mL, clear
• 储存温度: 2-8°C
• SMILES字符串: [s]1c2nccc(c2c3nc[n]([c](c31)=O)N4CCCCCC4)N(C)C
• InChI: 1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3
• InChI key: GYWGXEGOXODOQU-UHFFFAOYSA-N

说明

生化/生理作用

A-841720 is a potent, selective, non-competitive mGluR1 antagonist that displays greater than 30-fold selectivity over another Group I metabotopic glutamate receptor, mGluR5. The compound has potent analgesic properties, and can also diminish motor and cognitive activity.

A-841720 is a potent, selective, non-competitive mGluR1 antagonist.

特点和优势

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable