SML0595

A-286982

≥95% (HPLC)

• 别名: (2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one
• 经验公式（希尔记法）: C₂₄H₂₇N₃O₄S
• CAS号: 280749-17-9
• 分子量: 453.55
• UNSPSC代码: 12352200
• NACRES: NA.77

属性

• 质量水平: 100
• 方案: ≥95% (HPLC)
• 表单: powder
• 颜色: white to beige
• 溶解性: DMSO: 10 mg/mL, clear
• 储存温度: −20°C
• SMILES字符串: S(c2c(cc(cc2)\C=C\C(=O)N3CCN(CC3)C(=O)C)[N+](=O)[O-])c1c(cccc1)C(C)C
• InChI: 1S/C24H27N3O4S/c1-17(2)20-6-4-5-7-22(20)32-23-10-8-19(16-21(23)27(30)31)9-11-24(29)26-14-12-25(13-15-26)18(3)28/h4-11,16-17H,12-15H2,1-3H3/b11-9+
• InChI key: HTGGAYLWTDOFDK-PKNBQFBNSA-N

说明

生化/生理作用

A-286982 blocks binding of lymphocyte function-associated antigen-1 (LFA-1) with the cell adhesion molecule ICAM-1.

A-286982 blocks binding of lymphocyte function-associated antigen-1 (LFA-1) with the cell adhesion molecule ICAM-1. The IC₅₀ in a cell based assay is 35 nM.

其他说明

Air sensitive

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable