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方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 15 mg/mL (clear solution)
储存温度
2-8°C
SMILES字符串
OCCc1ccc(NC(=O)c2ccccc2NC(=O)c3ccc(cc3)[N+]([O-])=O)cc1
InChI
1S/C22H19N3O5/c26-14-13-15-5-9-17(10-6-15)23-22(28)19-3-1-2-4-20(19)24-21(27)16-7-11-18(12-8-16)25(29)30/h1-12,26H,13-14H2,(H,23,28)(H,24,27)
InChI key
LTWQQWSXYYXVGA-UHFFFAOYSA-N
生化/生理作用
KS-176 is a potent specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2) with no inhibition of the ATP binding cassette (ABC) transporters P-gp and MRP1.
KS-176 is a potent specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Ronald E Cannon et al.
Toxicological sciences : an official journal of the Society of Toxicology, 169(2), 475-484 (2019-03-05)
Tetrabromobisphenol A (TBBPA, CAS No. 79-94-7) is a brominated flame retardant used in 90% of epoxy coated circuit boards. Exposures to TBBPA can induce neurotoxicity and disrupt MAPK, estrogen, thyroid, and PPAR-associated signaling pathways. Because these pathways also regulate transporters
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