SML0228

Rc-Ome

≥98% (HPLC)

• 别名: (2E)-3-(2-hydroxy-5-methoxyphenyl)-1-(4-methoxyphenyl)-2-Propen-1-one, trans-6,4′-dimethoxyretrochalcone
• 经验公式（希尔记法）: C₁₇H₁₆O₄
• CAS号: 1073553-28-2
• 分子量: 284.31
• 分類程式碼代碼: 12352202
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: , light to dark yellow
• 溶解度: DMSO: ≥10 mg/mL
• 儲存溫度: 2-8°C

说明

應用

Rc-Ome may be used in GABA_A-mediated cell signaling studies.

生化／生理作用

Rc-OMe is a GABA_A PAM that distinguishes α₁β_2γ2s from α₁β₂ receptors. The compound has very weak potentiating effects on α₁β₂, but potentiates GABA-elicited currents of α₍₁₂₃₎β_2γ2s receptors, all with low μM EC₅₀s. Rc-OMe acts at a binding site that is distinct from BDZ, pentobarbital and loreclezole modulatory sites.

特點和優勢

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 象形圖: GHS09
• 訊號詞: Warning
• 危險聲明: H400
• 防範說明: P273 - P391 - P501
• 危險分類: Aquatic Acute 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable