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化驗
≥98% (HPLC)
形狀
powder
顏色
white to tan
溶解度
DMSO: ≥2 mg/mL (warmed to 60 °C)
儲存溫度
−20°C
SMILES 字串
Cc1cc(C)cc(OCC2CNC(=O)O2)c1
InChI
1S/C12H15NO3/c1-8-3-9(2)5-10(4-8)15-7-11-6-13-12(14)16-11/h3-5,11H,6-7H2,1-2H3,(H,13,14)
InChI 密鑰
IMWZZHHPURKASS-UHFFFAOYSA-N
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應用
Metaxalone may be used in cell signaling studies.
生化/生理作用
Metaxalone is a muscle relaxant. The mechanism of action of metaxalone in humans is not fully understood. It was suggested that it acts through general central nervous system depression.
Metaxalone is effective to relieve pain due to acute skeletal muscle pain caused due to musculoskeletal conditions and sprains.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Scientia pharmaceutica, 80(2), 353-366 (2012-08-17)
A simple, sensitive and reproducible reversed phase ultra performance liquid chromatography (RP-UPLC) coupled with a photodiode array detector method was developed for the quantitative determination of metaxalone (META) in pharmaceutical dosage forms. The method is applicable to the quantification of
Journal of analytical toxicology, 28(6), 537-541 (2004-11-02)
The case history and toxicological findings of a fatal multi-drug overdose involving metaxalone (Skelaxin) are presented. Gas-liquid chromatography with flame-ionization detection and gas chromatography-mass spectrometry were used to determine the following drug concentrations (mg/L) in aortic blood: 19 mg/L metaxalone;
Clinical therapeutics, 26(9), 1355-1367 (2004-11-09)
Low back pain is a leading reason for primary care visits. Many treatment options are available, but some lack scientific support. The aim of this review was to discuss the etiology of low back pain and the relative risks and
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