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About This Item
经验公式（希尔记法）:
C26H22O10 · xH2O
CAS号:
分子量:
494.45 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
化驗
≥98% (HPLC)
形狀
powder
顏色
yellow
溶解度
H2O: ≥19 mg/mL
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
O.OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2\C=C\c3ccc(O)c(O)c3
InChI
1S/C26H22O10.H2O/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15;/h1-12,23,27-31,33H,13H2,(H,34,35);1H2/b6-1+,10-5+;/t23-;/m1./s1
InChI 密鑰
XFUSRNNWIRPEDG-FYLUTCCGSA-N
應用
丹酚酸 A 水合物可用于细胞信号传导研究。
丹酚酸 A 水合物已被用作迷迭香酸衍生物，用于抑制人细胞系中的 DNA 聚合酶 e。
丹酚酸 A 水合物已被用作迷迭香酸衍生物，用于抑制人细胞系中的 DNA 聚合酶 e。
生化／生理作用
丹酚酸 A 作为活性氧的清除剂，减少白细胞对内皮细胞的粘附，抑制基质金属蛋白酶和炎症。它具有心脏保护作用，因为它抑制细胞凋亡，减少受损心脏组织中的脂质过氧化，并减少乳酸脱氢酶的泄漏。
丹酚酸 A 是最初从丹参中分离得到的具有细胞保护作用的抗氧化剂。研究发现它能减弱 PDGF 诱导的肝星状细胞 ROS 的形成，对异丙肾上腺素诱导的大鼠心肌损伤有保护作用。
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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Salvianolic acid A, an active compound present in Salvia miltiorrhiza, is a phenolic carboxylic acid derivative, ((2R)-3-(3,4-Dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl) ethenyl]-3,4-dihydroxyphenyl] prop-2-enoyl]oxypropanoic acid). The present study was performed to investigate the underlying mechanisms of anti-inflammatory effects with salvianolic acid A, specially focused on
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