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Merck
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Key Documents

SMB00608

Sigma-Aldrich

Potassium clavulanate: silicon dioxide (1:1)

别名:

Potassium clavulanate: silicon dioxide

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About This Item

分類程式碼代碼:
12352200

形狀

powder

顏色

off-white

溶解度

water: 1 mg/mL, clear to slightly hazy

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

作用方式

enzyme | inhibits

儲存溫度

2-8°C

一般說明

Material is a powdered mixture of 1 part potassium clavulanate to 1 part silicon dioxide.

生化/生理作用

Clavulanate is a β-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.

包裝

1G

儲存和穩定性

Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.

其他說明

Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.

象形圖

FlameHealth hazard

訊號詞

Danger

危險分類

Resp. Sens. 1 - Self-heat. 2 - Skin Sens. 1 - STOT RE 1 Inhalation

標靶器官

Lungs

安全危害

儲存類別代碼

4.2 - Pyrophoric and self-heating hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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B G Spratt et al.
Antimicrobial agents and chemotherapy, 12(3), 406-409 (1977-09-01)
Thienamycin and clavulanic acid are new beta-lactam derivatives with structures markedly different from those of penicillins or cephalosporins. Both derivatives had the same general mode of action as typical beta-lactam antibiotics since they bound to precisely the same proteins as
C Reading et al.
Antimicrobial agents and chemotherapy, 11(5), 852-857 (1977-05-01)
A novel beta-lactamase inhibitor has been isolated from Streptomyces clavuligerus ATCC 27064 and given the name clavulanic acid. Conditions for the cultivation of the organism and detection and isolation of clavulanic acid are described. This compound resembles the nucleus of

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