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Merck
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文件

SCP0156

Sigma-Aldrich

Gly-Arg-Ala-Asp-Ser-Pro (GRADSP)

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About This Item

经验公式（希尔记法）:
C23H39N9O10
分子量:
601.61
分類程式碼代碼:
12352209
NACRES:
NA.32

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥65%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Gly-Arg-Ala-Asp-Ser-Pro

一般說明

GRADSP, an integrin non-binding peptide, may be used as a negative control in studies with integrin-blocking peptides such as RGDS (Arg-Gly-Asp-Ser) and GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro).
Gly-Arg-Ala-Asp-Ser-Pro (GRADSP), an integrin non-binding peptide, may be used as a negative control in studies with integrin-blocking peptides such as Arg-Gly-Asp-Ser (RGDS) and Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP).

應用

Gly-Arg-Ala-Asp-Ser-Pro (GRADSP) has been used as a negative control to observe the role of the Arg-Gly-Asp (RGD)-binding integrins in Gal-3-mediated cell adhesion. It has also been used as a control peptide to block the RGD-dependent integrins/integrin signaling.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Major role of the extracellular matrix in airway smooth muscle phenotype plasticity
Dekkers BGJ
American Journal of Respiratory and Critical Care Medicine, 181(6), 556-565 (2010)
U Stäubli et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 18(9), 3460-3469 (1998-05-09)
The integrin antagonist Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) was applied by local ejection to one of two recording sites in hippocampal slices at various times before and after long-term potentiation (LTP) was induced at both sites with theta burst stimulation. Applications 10 min
Julia Dotterweich et al.
Cell communication and signaling : CCS, 12, 36-36 (2014-06-27)
CCN family member 1 (CCN1), also known as cysteine-rich angiogenic inducer 61 (CYR61), belongs to the extracellular matrix-associated CCN protein family. The diverse functions of these proteins include regulation of cell migration, adhesion, proliferation, differentiation and survival/apoptosis, induction of angiogenesis
Antonín Sedlář et al.
International journal of molecular sciences, 22(10) (2021-06-03)
Galectin-3 (Gal-3) is a β-galactoside-binding protein that influences various cell functions, including cell adhesion. We focused on the role of Gal-3 as an extracellular ligand mediating cell-matrix adhesion. We used human adipose tissue-derived stem cells and human umbilical vein endothelial

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