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生物来源
mouse
质量水平
重组
expressed in CHO cells
偶联物
unconjugated
抗体形式
affinity purified immunoglobulin
克隆
SAA0284, recombinant monoclonal
方案
>95% (SDS-PAGE)
表单
liquid
分子量
150 kDa
种属反应性
monkeypox virus
浓度
1 mg/mL
技术
ELISA: 1:2000-1:4000
neutralization: 0.01-10 μg/mL
颜色
colorless
pH值（酸碱度）
7.4
同位素/亚型
IgG2a, kappa
Protein ID登记号
UniProt登记号
运输
wet ice
储存温度
-65 to -96°C
靶向翻译后修饰
unmodified
一般描述
Anti-Monkeypox virus/MPXV M1R Antibody, clone SAA0284 is a monoclonal antibody produced in mouse. The monoclonal antibodies are IgG immunoglobulins, composed of two heavy chains and two light chains. Each chain contains a variable region that is specific for the target antigen, and a constant region that is responsible for binding to the B-cell receptor and other molecules involved in the immune response.
Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.
Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.
特异性
Monoclonal Anti-Monkeypox virus/MPXV M1R Antibody, clone SAA0284 binds to the surface of the monkeypox virus, preventing it from entering the cells of the host organism. This prevents the virus from replicating and spreading, thus providing protection against infection.
应用
ELISA,neutralization
包装
100µg per vial / 1 mg per vial
储存及稳定性
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
相关内容
Products and support for mpox research, offering world-class reagents for immunoassay and molecular assay development.
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