SAB5702884

Anti-Sprouty 2 Antibody, clone 10M8H1, Rabbit Monoclonal

• 别名: IGAN3, hSPRY2
• UNSPSC代码: 12352203
• NACRES: NA.46

属性

• 生物来源: rabbit
• 质量水平: 100
• 物料: colorless
• 克隆: 10M8H1, monoclonal
• 表单: liquid
• 分子量: 35 kDa
• 种属反应性: human, rat
• 浓度: 0.34 mg/mL
• 技术: immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 颜色: colorless
• 同位素/亚型: IgG
• 免疫原序列: GTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
• UniProt登记号: O43597
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... SPRY2(10253)

说明

一般描述

This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 216-315 of human Sprouty 2 (O43597).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB, IHC

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1