生物来源
rabbit
质量水平
物料
colorless
克隆
9K6H0, monoclonal
表单
liquid
分子量
25 kDa
种属反应性
rat, human, rat
浓度
0.2 mg/mL
技术
immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000
颜色
colorless
同位素/亚型
IgG
免疫原序列
YFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... GRB2(2885)
一般描述
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 118-217 of human GRB2 (P62993).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
应用
WB, IHC, IF/ICC, IP
储存分类代码
10 - Combustible liquids
WGK
WGK 1
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