SAB5702643

Anti-PDZK1 Antibody, clone 5C1D3, Rabbit Monoclonal

• 别名: CAP70, CLAMP, NHERF-3, NHERF3, PDZD1
• UNSPSC代码: 12352203
• NACRES: NA.46

属性

• 生物来源: rabbit
• 质量水平: 100
• 物料: colorless
• 克隆: 5C1D3, monoclonal
• 表单: liquid
• 分子量: 70 kDa
• 种属反应性: human, rat, rat
• 浓度: 0.49 mg/mL
• 技术: immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 颜色: colorless
• 同位素/亚型: IgG
• 免疫原序列: EDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM
• UniProt登记号: Q5T2W1
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... PDZK1(5174)

说明

一般描述

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 420-519 of human PDZK1 (Q5T2W1).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB, IF/ICC

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1