SAB5702282

Anti-SOCS1 Antibody, clone 5T6Z10, Rabbit Monoclonal

• 别名: SOCS1,CIS1,CISH1,JAB,SOCS-1,SSI-1,SSI1,TIP3,TIP-3
• UNSPSC代码: 12352203
• NACRES: NA.46

属性

• 生物来源: rabbit
• 质量水平: 100
• 物料: colorless
• 克隆: 5T6Z10, monoclonal
• 表单: liquid
• 种属反应性: rat, human, rat
• 浓度: 1 mg/mL
• 技术: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200
• 颜色: colorless
• 同位素/亚型: IgG
• 免疫原序列: MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGT
• UniProt登记号: O15524
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... SOCS1(8651)

说明

一般描述

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOCS1 (NP_003736.1).

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

应用

IHC, IF/ICC

安全信息

• 象形图: GHS07,GHS09
• 警示用语：: Warning
• 危险声明: H317,H411
• 预防措施声明: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危险分类: Aquatic Chronic 2 - Skin Sens. 1
• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 3