SAB5702072

Anti-SDHB Antibody, clone 9S1A0, Rabbit Monoclonal

• 别名: CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
• UNSPSC代码: 12352203
• NACRES: NA.46

属性

• 生物来源: rabbit
• 质量水平: 100
• 物料: colorless
• 克隆: 9S1A0, monoclonal
• 表单: liquid
• 分子量: 32 kDa
• 种属反应性: rat, rat, human
• 浓度: 0.19 mg/mL
• 技术: western blot: 1:500 - 1:2000
• 颜色: colorless
• 同位素/亚型: IgG
• 免疫原序列: DGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV
• UniProt登记号: P21912
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... SDHB(6390)

说明

一般描述

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 181-280 of human SDHB (P21912).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1