SAB5701937

Anti-Phospho-MCM2-S139 antibody produced in rabbit

• UNSPSC代码: 12352203
• NACRES: NA.43

属性

• 生物来源: rabbit
• 质量水平: 100
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: liquid
• 种属反应性: human, rat, mouse
• 浓度: 0.34 mg/mL
• 技术: western blot: 1:500-1:2000
• UniProt登记号: P49736
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: phosphorylation (pSer139)
• 基因信息: human ... MCM2(4171)

说明

一般描述

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

免疫原

A synthetic phosphorylated peptide around S139 of human MCM2.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable