SAB5701794

Anti-Phospho-Caveolin-1-Y14 antibody produced in rabbit

• UNSPSC代码: 12352203
• NACRES: NA.43

属性

• 生物来源: rabbit
• 质量水平: 100
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: liquid
• 种属反应性: mouse, human, rat
• 浓度: 1.59 mg/mL
• 技术: western blot: 1:500-1:2000
• UniProt登记号: Q03135
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: phosphorylation (pTyr14)
• 基因信息: human ... CAV1(857)

说明

一般描述

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

免疫原

A synthetic phosphorylated peptide around Y14 of human Caveolin-1 (NP_001744.2).

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable