SAB5700476

Anti-Phospho-MAP3K7-T187 antibody produced in rabbit

• 别名: CSCF, FMD2, MAP3K7, MEKK7, TAK1, TGF1a
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: 53; 56; 64; 67
• 种属反应性: mouse, human
• 浓度: 0.62mg/ml
• 技术: western blot: 1:500-1:2000
• UniProt登记号: O43318
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: phosphorylation (pThr187)
• 基因信息: human ... MAP3K7(6885)

说明

一般描述

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

免疫原

A synthetic phosphorylated peptide around T187 of human MAP3K7 (NP_003179.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable