SAB5700316

Anti-Phospho-MAX-S11 antibody produced in rabbit

• 别名: MAX, bHLHd4
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: 11; 12; 15; 17; 18; 9
• 种属反应性: human
• 浓度: 0.20 mg/ml
• 技术: immunofluorescence: 1:50-1:200; western blot: 1:500-1:2000
• UniProt登记号: P61244
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: phosphorylation (pSer11)
• 基因信息: human ... MAX(4149)

说明

一般描述

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

免疫原

A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable