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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous glycerol solution
分子量
antigen predicted mol wt 33 kDa
物種活性
mouse, human
濃度
250 μg/mL
技術
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
mouse ... Ing1(26356)
一般說明
Inhibitor of growth-family member 1 (ING1) possesses plant homeodomains (PHDs). The gene ID of the protein is 26356.
特異性
Detects a ~33 kDa protein corresponding to the molecular mass of p33 ING1 on SDS PAGE immunoblots.
免疫原
Mouse p33 ING1 N-terminal peptide –KLH conjugates
生化／生理作用
Inhibitor of growth-family member 1 (ING1) may take part in chromatin remodeling. It is a part of histone acetyltransferase complex and acts as an epigenetic modulator. Like the other members of its family, ING1 also functions as a tumor suppressor.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
TBS, 50% glycerol, 0.09% sodium azide
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Masato Takahashi et al.
Cancer research, 62(8), 2203-2209 (2002-04-17)
The candidate tumor suppressor p33(ING1) plays an important role in inducinggrowth arrest at G(0)-G(1) phase of the cell cycle and/or promoting apoptosis in cancerous cells. p33(ING1) is reported to act as a transcriptional cofactor by associating with tumor suppressor p53
Uma Karthika Rajarajacholan et al.
PLoS biology, 11(3), e1001502-e1001502 (2013-03-09)
The INhibitor of Growth (ING) proteins act as type II tumor suppressors and epigenetic regulators, being stoichiometric members of histone acetyltransferase and histone deacetylase complexes. Expression of the alternatively spliced ING1a tumor suppressor increases >10-fold during replicative senescence. ING1a overexpression
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