共軛
Allophycocyanin conjugate
品質等級
抗體產品種類
primary antibodies
無性繁殖
HM47, monoclonal
形狀
buffered aqueous solution
物種活性
( Chicken), dog, ( Rabbit), ( Guinea pig)
技術
flow cytometry: suitable
同型
IgG1κ
UniProt登錄號
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... CD79A(973)
一般說明
CD79a (Ig alpha, MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.
特異性
The mouse monoclonal antibody HM47 reacts with intracellular domain of CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms.
免疫原
Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a
外觀
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
準備報告
Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
儲存和穩定性
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
其他說明
The antibody solution should be gently mixed before use.
未找到合适的产品？
试试我们的产品选型工具.
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门