SAB4700562

Monoclonal Anti-Cd86-FITC antibody produced in rat

clone GL-1, purified immunoglobulin, buffered aqueous solution

• UNSPSC代码: 12352203
• NACRES: NA.44

属性

• 生物来源: rat
• 偶联物: FITC conjugate
• 抗体形式: purified immunoglobulin
• 抗体产品类型: primary antibodies
• 克隆: GL-1, monoclonal
• 表单: buffered aqueous solution
• 种属反应性: mouse
• 浓度: 0.5 mg/mL
• 技术: flow cytometry: suitable
• 同位素/亚型: IgG2a
• NCBI登记号: NM_019388.3
• UniProt登记号: P42082
• 运输: wet ice
• 储存温度: 2-8°C
• 基因信息: mouse ... Cd86(12524)

说明

一般描述

Cluster of differentiation 86 (CD86), also known as B7-2, is encoded by the gene mapped to human chromosome 3q13.33. CD86 is a co-stimulatory molecule expressed on various immune cells. The encoded protein belongs to the immunoglobulin (Ig) superfamily.

The rat monoclonal antibody GL-1 reacts with CD86 (B7-2), a 70-80 kDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.

免疫原

LPS-activated CBA/Cs mouse splenic B cells

应用

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

生化/生理作用

Cluster of differentiation 86 (CD86) plays a vital role in immune responses. Mutations in the gene leads to the development of pneumonia-induced sepsis by downregulating CD86 gene expression in monocytes. Additionally, genetic variation in the gene increases the risk of susceptibility to colorectal cancer.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable