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生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 60 kDa
种属反应性
mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
acetylation (Lys310)
基因信息
human ... RELA(5970)
一般描述
Anti-NF-κB p65 (Acetyl-Lys310) Antibody detects endogenous levels of total NF-κB p65 (Acetyl-Lys310) protein.
RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) codes for the important constituent of the NF-κB (nuclear factor κ-B) complex. It is located on human chromosome 11q13.1. It is also called as nuclear factor κB subunit 3 (NFKB3).
RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) codes for the important constituent of the NF-κB (nuclear factor κ-B) complex. It is located on human chromosome 11q13.1. It is also called as nuclear factor κB subunit 3 (NFKB3).
免疫原
The antiserum was produced against synthesized peptide derived from human NF-kappaB p65 around the acetylated site of Lys310.
Immunogen Range: 275-324
Immunogen Range: 275-324
应用
Anti-NF-κB p65 (Acetyl-Lys310) antibody has been used in western blotting.
生化/生理作用
RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) participates in nuclear factor κ-B (NFKB) signaling pathway. It also controls inflammation. Alterations in the gene results in schizophrenia and startle reactions.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Zheng Y, et al.
Stroke, 46(2), 485-485 (2015)
Yun Zheng et al.
Stroke, 46(2), 485-491 (2014-12-20)
17β-estradiol (E2) has been reported to reduce bleeding and brain injury in experimental intracerebral hemorrhage (ICH) model. However, it is not clear if E2 can prevent early hematoma expansion (HE) induced by hyperglycemia in acute ICH. The aim of this
Variants of the RELA gene are associated with schizophrenia and their startle responses.
Hashimoto R, et al.
Neuropsychopharmacology, 36(9), 1921-1921 (2011)
Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.
Pare G, et al.
PLoS Genetics, 7(4), e1001374-e1001374 (2011)
Chun-Cheih Chao et al.
Cell, 179(7), 1483-1498 (2019-12-10)
Metabolism has been shown to control peripheral immunity, but little is known about its role in central nervous system (CNS) inflammation. Through a combination of proteomic, metabolomic, transcriptomic, and perturbation studies, we found that sphingolipid metabolism in astrocytes triggers the
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