SAB4300561
Anti-SMAD1 (Ab-465) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-BSP1 antibody produced in rabbit, Anti-JV4-1 antibody produced in rabbit, Anti-JV41 antibody produced in rabbit, Anti-MADH1 antibody produced in rabbit, Anti-SMAD family member 1 antibody produced in rabbit
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所有图片(2)
About This Item
分類程式碼代碼:
12352203
NACRES:
NA.41
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
~55 kDa
物種活性
mouse, rat, human
濃度
1 mg/mL
技術
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同型
IgG
免疫原序列
(I-S-S-V-S)
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... SMAD1(4086)
一般說明
Smad1 (SMAD family member 1) is a transcriptional activator, that is located on chromosome 4q31.
免疫原
Peptide sequence around aa. 461-465 (I-S-S-V-S), according to the protein SMAD1.
生化／生理作用
SMAD1 (SMAD family member 1) protein has a major role in disease development, hence it acts as a biologic prognostic factor in diseases. The miR-345 repress the multiplication, invasion and migration of prostate cancer by downregulating Smad1.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
標靶描述
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
外觀
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia
Witkowska M, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(3) (2017)
An interstitial 4q31.21q31.22 microdeletion associated with developmental delay: case report and literature review
Vlaikou AM, et al.
Cytogenetic and genome research, 142(4), 227-238 (2014)
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
Fuentealba LC, et al.
Cell, 131(5), 980-993 (2007)
MiR-345 suppresses proliferation, migration and invasion by targeting Smad1 in human prostate cancer
Chen QG, et al.
Journal of Cancer Research and Clinical Oncology, 142(1), 213-224 (2016)
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