SAB4300438

Anti-ZAP70 (Ab-493) antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-FLJ17670 antibody produced in rabbit, Anti-FLJ17679 antibody produced in rabbit, Anti-SRK antibody produced in rabbit, Anti-STD antibody produced in rabbit, Anti-zeta-chain (TCR) associated protein kinase 70kDa antibody produced in rabbit
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: ~70 kDa
• 种属反应性: rat, mouse, human
• 浓度: 1 mg/mL
• 技术: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• 同位素/亚型: IgG
• 免疫原序列: (S-Y-Y-T-A)
• NCBI登记号: NP_001070.2
• UniProt登记号: P43403
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... ZAP70(7535)

说明

免疫原

Peptide sequence around aa. 491-495 (S-Y-Y-T-A), according to the protein ZAP70.

特点和优势

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目标描述

ZAP70 is a 70-kD tyrosine phosphoprotein that associates with the zeta chain and undergoes tyrosine phosphorylation following TCR stimulation. The ZAP70 gene is expressed in T- and natural KILLER cells. Protein-Tyrosine Kinases (PTKs) play an integral role in T-cell activation. Stimulation of the T-cell antigen receptor results in tyrosine phosphorylation of a number of cellular substrates. One of these is the TCR-zeta chain, which can mediate the transduction of extracellular stimuli into cellular effector functions.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable