SAB4300419
Anti-CDKN1A (Ab-145) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-CAP20 antibody produced in rabbit, Anti-CDKN1 antibody produced in rabbit, Anti-CIP1 antibody produced in rabbit, Anti-MDA-6 antibody produced in rabbit, Anti-cyclin-dependent kinase inhibitor 1A (p21, Cip1) antibody produced in rabbit
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About This Item
分類程式碼代碼:
12352203
NACRES:
NA.41
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
~21 kDa
物種活性
human
濃度
1 mg/mL
技術
western blot: 1:500-1:1000
同型
IgG
免疫原序列
(R-Q-T-S-M)
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... CDKN1A(1026)
免疫原
Peptide sequence around aa. 143-147 (R-Q-T-S-M), according to the protein CDKN1A.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
標靶描述
May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.
外觀
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Xiaojun Shu et al.
Molecular medicine reports, 19(6), 5195-5202 (2019-05-07)
MicroRNAs (miRNAs) are considered to be critical mediators of gene expression with respect to tumor progression, although their role in ischemia‑induced angiogenesis is poorly characterized, including in peripheral arterial disease (PAD). Furthermore, the underlying mechanism of action of specific miRNAs
Xiang Li et al.
Oxidative medicine and cellular longevity, 2019, 9706792-9706792 (2019-03-27)
Multiple signaling pathways including ERK, PI3K-Akt, and NF-κB, which are essential for onset and development of cancer, can be activated by intracellularly sustained high levels of H2O2 provided by elevated activity and expression of copper/zinc superoxide dismutase (SOD1) that catalyzes
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