SAB4300031

Anti-phospho-GATA1 (pSer³¹⁰) antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-ERYF1 antibody produced in rabbit, Anti-GATA binding protein 1 (globin transcription factor 1) antibody produced in rabbit, Anti-GF-1 antibody produced in rabbit, Anti-GF1 antibody produced in rabbit, Anti-NFE1 antibody produced in rabbit
• MDL號碼: MFCD02096392
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: ~43 kDa
• 物種活性: rat, mouse, human
• 濃度: 1 mg/mL
• 技術: indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• 同型: IgG
• 免疫原序列: (K-A-SP-G-K)
• NCBI登錄號: NP_002040.1
• UniProt登錄號: P15976
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pSer310)
• 基因資訊: human ... GATA1(2623)

说明

一般說明

GATA binding protein 1 (GATA1) is a key hematopoietic transcription factor. It is encoded by the gene mapped to human chromosome Xp11.23 and it belongs to the GATA transcription factor family.

免疫原

Peptide sequence around phosphorylation site of serine 310 (K-A-S(p)-G-K), according to the protein GATA1.

生化／生理作用

GATA binding protein 1 (GATA1) plays a crucial role in erythroid and megakaryocyte differentiation and proliferation. It modulates the expression of genes and acts as an E-cadherin repressor. Mutations in the GATA1 gene have been linked to transient abnormal myelopoiesis (TAM) and myeloid leukemia of DS (ML-DS). The protein has anti-apoptotic functions in breast cancer.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable