SAB4200639

Monoclonal Anti-DHX9/RHA antibody produced in rat

clone 8E3, purified from hybridoma cell culture

• 别名: Anti-ATP−dependent RNA helicase A, Anti-ATP-dependent RNA helicase A, Anti-DDX9, Anti-DEAD/H (Asp−Glu−Ala−Asp/His) box polypeptide 9, Anti-DEAH (Asp−Glu−Ala−His) box polypeptide 9, Anti-DEAH (Asp-Glu-Ala-His) box helicase 9, Anti-DEAH (Asp-Glu-Ala-His) box polypeptide 9, Anti-DEAH box protein 9, Anti-DHX9, Anti-Ddx9, Anti-HEL-5, Anti-LKP, Anti-NDH2, Anti-NDHII, Anti-Nuclear DNA helicase II (NDHII), Anti-leukophysin, Anti-mHEL-5, Anti-nuclear DNA helicase II, RHA, RNA helicase A
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rat
• 质量水平: 200
• 抗体形式: purified immunoglobulin
• 抗体产品类型: primary antibodies
• 克隆: 8E3, monoclonal
• 表单: buffered aqueous solution
• 种属反应性: mouse, hamster, rat, bovine, canine, monkey, human
• 浓度: ~1 mg/mL
• 技术: immunoblotting: 1-2 μg/mL using using whole extracts of HeLa cells.; immunofluorescence: 5-10 μg/mL using using HeLa cells
• 同位素/亚型: IgG1
• UniProt登记号: Q08211
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: Monkey ... DHX9(715453) ; canine ... DHX9(480032) ; human ... DHX9(1660) ; mouse ... Dhx9(13211) ; rat ... Dhx9(304859)

说明

一般描述

DHX9 (DEAH (Asp-Glu-Ala-His) box helicase 9) also known as RNA Helicase A, nuclear DNA helicase II (NDHII), belongs to the DExD/H family of helicase superfamily 2, that exhibits both RNA and DNA helicase activity in an ATP dependent reaction.

免疫原

synthetic peptide corresponding to the N-terminal region of mouse DHX9

应用

Monoclonal Anti-DHX9/RHA antibody produced in rat has been used in immunoblotting and immunofluorescence.

生化/生理作用

DHX9 (DEAH (Asp-Glu-Ala-His) box helicase 9) is involved in RNA metabolism including RNA secondary structure rearrangement, RNA-protein interactions, RNA turnover, ribosome biogenesis, translation and small RNA metabolism. It participates in the replication cycles of retroviruses and other RNA viruses. DHX9 is implicated in multiple steps of HIV-1 replication, including transcription, export of unspliced viral RNA from the nucleus, translation, particle assembly and reverse transcription.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable