生物来源
mouse
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
W49.1, monoclonal
表单
buffered aqueous solution
分子量
antigen ~85 kDa
种属反应性
human
浓度
~1.0 mg/mL
技术
flow cytometry: 5-10 μg/test using Jurkat cells
immunoblotting: 20 μg/mL using total cell extracts of HEK-293T cells overexpressing WDR49
immunocytochemistry: suitable
immunofluorescence: 10-20 μg/mL using HeLa cells
同位素/亚型
IgG1
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... WDR49(151790)
一般描述
Monoclonal Anti-WDR49 (mouse IgG1 isotype) is derived from the hybridoma W49.1 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide. WD repeat-containing protein 49 (WDR49) is expressed as two isoforms. It is located on the human chromosome at 3q26.1.
特异性
Monoclonal Anti-WDR49 recognizes human WDR49.
免疫原
synthetic peptide corresponding to an internal sequence of human WDR49
应用
Monoclonal Anti-WDR49 antibody produced in mouse may be used in:
- immunoblotting
- flow cytometry
- immunocytochemistry
- immunofluorescence
生化/生理作用
WD repeat-containing protein 49 (WDR49) is deleted in liver cancer as well as fatal, disomy 3 uveal melanoma. It may play a role as a tumor suppressor gene.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
储存及稳定性
For extended storage, freeze at -20 °C in working aliquots. Repeated freezing and thawing,orstorage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Sex-Specific Transcriptome Differences in Substantia Nigra Tissue: A Meta-Analysis of Parkinson?s Disease Data
Mariani E, et al.
Genes, 9(6), 275-275 (2018)
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