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Merck

SAB4200231

Sigma-Aldrich

Anti-DCAL-1 antibody, Mouse monoclonal

clone UW50, purified from hybridoma cell culture

别名:

Anti-C-type lectin-like 1, Anti-CLECL1

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

偶联物

unconjugated

抗体形式

purified from hybridoma cell culture

抗体产品类型

primary antibodies

克隆

UW50, monoclonal

表单

buffered aqueous solution

种属反应性

human

浓度

~1.0 mg/mL

技术

flow cytometry: 0.25-0.50 μg/test using 1x106 human Raji cells

同位素/亚型

IgM

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... CLECL1(160365)

一般描述

Dendritic cell-associated lectin-1 (DCAL-1), also known as C-type lectin-like-1 (CLECL1), is a novel C-type lectin-like molecule, encoded by the gene mapped to human chromosome 12p13.31. The encoded protein is exclusively expressed in human hematopoietic cells, in particular at high levels in dendritic cells (DCs) and B cells.
Monoclonal Anti-DCAL-1 (mouse IgM isotype) is derived from the hybridoma UW50 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice, immunized with a human DCAL-1 fusion protein

特异性

Monoclonal Anti-DCAL-1 recognizes human DCAL-1.

免疫原

human DCAL-1 fusion protein.

应用

Monoclonal Anti-DCAL-1 antibody produced in mouse may be used in flow cytometry.

生化/生理作用

Dendritic cell-associated lectin-1 (DCAL-1) functions as a T-cell co-stimulatory molecule and increases interleukin-4 secretion. The encoded protein is also implicated in the regulation of the immune response.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

储存及稳定性

For continuous use, store at 2-8°C for up to one month. For extended storage, freeze at -20°C in working aliquots. Repeated freezing and thawing,or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4.
Ryan EJ
Journal of Immunology, 169, 5638-5648 (2002)
Elizabeth J Ryan et al.
Human immunology, 70(1), 1-5 (2008-11-26)
Dendritic cell-associated lectin-1 (DCAL-1), also known as C-type lectin-like-1 (CLECL1), is a novel C-type lectin-like molecule expressed by antigen presenting cells including dendritic cells (DCs). Here we report that incubation of immature DCs (iDCs) with an anti-DCAL-1 monoclonal antibody (mAb)

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