SAB4200160

Anti-Synaptotagmin 7 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 别名: Anti-IPCA-7, Anti-PCANAP7, Anti-SYT-VII, Anti-SYT7
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: ~45 kDa
• 种属反应性: mouse, human
• 增强验证: recombinant expression; Learn more about Antibody Enhanced Validation
• 浓度: ~1.0 mg/mL
• 技术: western blot: 1-2 μg/mL using mouse brain extracts (S1 fraction) and HEK-293T cell lysates expressing human synaptotagmin 7
• UniProt登记号: O43581
• 运输: dry ice
• 储存温度: −20°C
• 基因信息: human ... SYT7(9066) ; mouse ... Syt7(54525)

说明

一般描述

Synaptotagmin 7, also known as Syt7, is a transmembrane Ca²⁺ binding protein. It belongs to synaptotagmin family of proteins. Syt7 contains a single transmembrane domain, a variable linker sequence and C2A and C2B Ca²⁺-binding domains. Syt7 is ubiquitously expressed during development but is later restricted to dividing cells, postmitotic neurons and neuroendocrine cells.

应用

Anti-Synaptotagmin 7 antibody produced in rabbit has been used in immunoblotting.

生化/生理作用

Synaptotagmins regulates membrane or vesicular trafficking, including synaptic vesicle (SV) exocytosis. Synaptotagmin 7 plays a vital role in regulation of Ca²⁺-dependent lysosome exocytosis. Syt7 is expressed in pancreatic β-cells and has been suggested to function as a Ca²⁺ sensor regulating insulin secretion. Knockout of Syt7 in mice results in impaired insulin secretion and glucose intolerance.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable