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Merck

SAB4100383

Sigma-Aldrich

Monoclonal Anti-TMOD1 antibody produced in mouse

clone TMOD1-A328, culture supernatant

别名:

Anti-D9S57E, Anti-ETMOD, Anti-TMOD, Anti-tropomodulin 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

TMOD1-A328, monoclonal

形狀

aqueous solution

分子量

antigen predicted mol wt 40.4 kDa

物種活性

human

技術

western blot: suitable

同型

IgG2b

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... TMOD1(7111)

一般說明

Tropomodulin 1 (TMOD1) is an actin-capping protein, which is expressed in the cardiac muscle and in slow-twitch muscle fibers. It possesses two actin- and two tropomyosin (TM)-binding regions. The gene encoding this protein is localized on human chromosome 9q.

免疫原

TMOD1 purified recombinant protein

生化/生理作用

Tropomodulin 1 (TMOD1) prevents the elongation and depolymerization of actin filaments by binding to the slowly growing pointed end of the actin filament. It has been associated with triple-negative breast cancers (TNBC). TMOD1 may act as a stabilizer of β-catenin.

外觀

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Tropomodulin 1 Expression Driven by NF-?B Enhances Breast Cancer Growth
Taku Ito-Kureha
Cancer Research, 75(1) (2015)
Leucine 135 of Tropomodulin-1 Regulates Its Association with Tropomyosin, Its Cellular Localization, and the Integrity of Sarcomeres*
Kimi Y and Larry Kedes
The Journal of Biological Chemistry (2006)
Complete trisomy 9 with unusual phenotypic associations: Dandy-Walker malformation, cleft lip and cleft palate, cardiovascular abnormalities
Gabriele Tonni, et.al
Taiwanese Journal of Obstetrics & Gynecology, 53(4), 592-597 (2014)
Mechanism of actin filament pointed end capping by tropomodulin
Jampani Nageswara Rao
Science, 345(6195), 463-467 (2014)
Complete trisomy 9 with unusual phenotypic associations: Dandy-Walker malformation, cleft lip and cleft palate, cardiovascular abnormalities
GabrieleTonni
Taiwanese Journal of Obstetrics & Gynecology, 53(4), 592-597 (2014)

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