生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
42 kDa
种属反应性
dog, horse, human, mouse, bovine, rabbit, rat
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ATP6V1C1(528)
一般描述
ATP6V1C1 (ATPase H+ transporting V1 subunit C1) is a subunit and regulator of V-ATPase (vacuolar ATPase).
免疫原
Synthetic peptide directed towards the N terminal region of human ATP6V1C1
生化/生理作用
ATP6V1C1 (ATPase H+ transporting V1 subunit C1) is overexpressed in breast cancer, where it modulates the actin structure in a way that it promotes metastasis. This gene is up-regulated in oral squamous cell carcinoma (OSCC).
序列
Synthetic peptide located within the following region: ldafvegvvkkvaqymadvledskdkvqenllangvdlvtyitrfqwdma
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Atp6v1c1 may regulate filament actin arrangement in breast cancer cells.
Cai M et al
PLoS ONE, 9(1), e84833-e84833 (2014)
Immunohistochemical localization of C1 subunit of V-ATPase (ATPase C1) in oral squamous cell cancer and normal oral mucosa.
Garcia-Garcia A et al
Biotechnic & Histochemistry, 87(2), 133-139 (2012)
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