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Merck

SAB1409291

Sigma-Aldrich

Monoclonal Anti-CUEDC1 antibody produced in mouse

clone 4F9, purified immunoglobulin, buffered aqueous solution

别名:

DKFZp547L163, FLJ20739

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

4F9, monoclonal

形狀

buffered aqueous solution

分子量

antigen 68.7 kDa

物種活性

human

技術

indirect ELISA: suitable
western blot: 1-5 μg/mL

同型

IgG2aκ

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CUEDC1(404093)

免疫原

CUEDC1 (NP_060419.1, 1 a.a. ~ 386 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQAMDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYEDSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPPTPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNAGGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSEDALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAASTANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ

生化/生理作用

CUEDC1 (CUE domain containing 1) might be involved in protein trafficking and degradation. Changes in this gene are linked with early stage cervical cancer. It is highly methylated in the placental tissue of preeclampsia patients. CUEDC1 is suggested to control trophoblast invasion by participating in the TGF (transforming growth factor)-β/Smad (mothers against decapentaplegic homolog) signaling pathway. The gene is mapped to human chromosome 17q23.

外觀

Solution in phosphate buffered saline, pH 7.4

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Y-H Yan et al.
European review for medical and pharmacological sciences, 17(22), 3083-3094 (2013-12-05)
Preeclampsia is a complication of pregnancy that severely threatens the health of the mother and infant, yet the mechanism of pathogenesis remains unclear. In this article, gene array technology was applied to identify the genes related to the pathogenesis of

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