SAB1403470

Monoclonal Anti-BNIPL, (N-terminal) antibody produced in mouse

clone 2C8, purified immunoglobulin, buffered aqueous solution

• 别名: BNIP-S, BNIPL-1, BNIPL-2, BNIPL1, BNIPL2, PP753
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: mouse
• 偶联物: unconjugated
• 抗体形式: purified immunoglobulin
• 抗体产品类型: primary antibodies
• 克隆: 2C8, monoclonal
• 表单: buffered aqueous solution
• 分子量: antigen ~56.36 kDa
• 种属反应性: human
• 技术: indirect ELISA: suitable; western blot: 1-5 μg/mL
• 同位素/亚型: IgG2aκ
• NCBI登记号: BC027868
• UniProt登记号: Q7Z465
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... BNIPL(149428)

说明

一般描述

The gene BNIPL (Bcl-2/adenovirus E1B 19kDa interacting protein 2-like) encodes a protein containing BNIP-2 and Cdc42GAP homology (BCH) domain and has a molar mass of 19kDa. It is abundantly expressed in human placenta and lung.

免疫原

BNIPL (AAH27868, 1 a.a. ~ 275 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MRKRLSAPELRLSLTKGPGNDGASPTQSAPSSPDGSSDLEIDELETPSDSEQLDSGHEFEWEDELPRAEGLGTSETAERLGRGCMWDVTGEDGHHWRVFRMGPREQRVDMTVIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDLHGSGGT

生化/生理作用

The gene BNIPL (Bcl-2/adenovirus E1B 19 kDa interacting protein 2-like) encodes a protein of the BNIPL family that functions in the apoptotic pathway. The BCH (BNIP-2 and Cdc42GAP homology) domain plays a crucial role by interacting with Bcl-2 and Cdc42GAP and inducing cell death. It serves as a linker protein in Bcl-2 pathway for DNA fragmentation. It also participates in Cdc42 (cell division control) signaling for changes in cell morphology and membrane blebbing during apoptosis. It facilitates invasion and cancer metastasis.

外形

Solution in phosphate buffered saline, pH 7.4

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable