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Merck
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主要文件

SAB1303498

Sigma-Aldrich

ANTI-MBTD1 (C-TERM) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

MBT domain-containing protein 1, MBTD1

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

70547 Da

种属反应性

mouse, human

技术

immunohistochemistry: 1:50-1:100
western blot: 1:1000

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

一般描述

MBTD1 (Mbt domain containing 1) is a member of Polycomb group (PcG) of proteins consisting of four MBT repeats, which form an asymmetric rhomboid architecture and a FCS-type zinc finger at the N-terminus end with putative regulatory function.

应用

ANTI-MBTD1 (C-TERM) antibody produced in rabbit is suitable for immunohistochemistry at a dilution of 1:50-1:100 and western blot at a dilution of 1:250-1:500

生化/生理作用

MBTD1 (Mbt domain containing 1) is involved in the developmental regulation. MBT group of proteins help to suppress the transcriptional expression of developmental control genes. It has been studied that MBT domain of the protein binds to mono-methylated and dimethylated ′Lys-20′ on histone H4 during the determination of histone binding ability of MBTD1.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jitka Eryilmaz et al.
PloS one, 4(10), e7274-e7274 (2009-10-21)
The Polycomb group (PcG) of proteins is a family of important developmental regulators. The respective members function as large protein complexes involved in establishment and maintenance of transcriptional repression of developmental control genes. MBTD1, Malignant Brain Tumor domain-containing protein 1

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