SAB1300705

Anti-SNURF (center) antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

• 别名: Anti-SNRPN upstream reading frame protein, Anti-SNURF
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 200
• 偶联物: unconjugated
• 抗体形式: saturated ammonium sulfate (SAS) precipitated
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 种属反应性: human
• 技术: indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI登记号: NP_005669
• UniProt登记号: Q9Y675
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... SNURF(8926)

说明

一般描述

SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5′ untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5′ UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.

免疫原

SNURF (NP_005669, 9-42)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human SNURF.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: nwg
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable