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生物源
rabbit
共軛
unconjugated
抗體表格
saturated ammonium sulfate (SAS) precipitated
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human
技術
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... KLF4(9314)
一般說明
Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2.
免疫原
KLF4 (NP_004226.3, )
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.
生化/生理作用
Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells.
外觀
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Advances in Reprogramming Somatic Cells to Induced Pluripotent Stem Cells
Stem Cell Reviews (2010)
KLF4 is a Novel Candidate Tumor Suppressor Gene in Pancreatic Ductal Carcinoma
The American Journal of Pathology (2011)
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
The Journal of Biological Chemistry (2007)
Dynamic down-regulation of Kruppel-like factor 4 in colorectal adenoma-carcinoma sequence.
Journal of Cancer Research and Clinical Oncology (2008)
Kruppel-like factor 4 (KLF4): What we currently know.
Gene (2017)
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