SAB1300567

Anti-SIGLEC11 (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 别名: Anti-Sialic acid-binding Ig-like lectin 11
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: IgG fraction of antiserum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000
• NCBI登錄號: NP_443116
• UniProt登錄號: Q96RL6
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SIGLEC11(114132)

说明

一般說明

SIGLECs are a family of cell surface lectins defined by shared structural motifs in the first 2 immunoglobulin (Ig)-like domains and by their ability to recognize sialic acids via the first Ig V set domain. SIGLEC11 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, this protein may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

免疫原

SIGLEC11 (NP_443116, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SIGLEC11.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable