SAB1300008

Anti-Hrk BH3 Domain antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 别名: Anti-Activator of apoptosis harakiri, Anti-BCL2-interacting protein, Anti-Neuronal death protein DP5
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: IgG fraction of antiserum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000
• NCBI登錄號: NP_003797
• UniProt登錄號: O00198
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... HRK(8739)

说明

一般說明

Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL.

免疫原

HRK (NP_003797, 20-60)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 30-50 of human Hrk.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable