化驗
≥97% (HPLC)
儲存溫度
−20°C
InChI 密鑰
ILCVKEBXPLEGOY-ZLFMSJRASA-N
Amino Acid Sequence
Glp-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Leu-Glu-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2
一般說明
Sauvagine is a polypeptide derived from the frog skin. It belongs to the CRH (corticotropin releasing factor) family. Sauvagine is made of 40 amino acids. It may also be found in the brain of mammals.
生化／生理作用
A peptide related to CRF and urotensin 1 that was first isolated from the skin of the frog Phyllomedusa sauvagei. Potent releaser of ACTH and β-endorphin from the anterior pituitary.
Sauvagine helps to liberate ACTH (adrenocorticotropic hormone) from the pituitary cells of rat. It has several important functions in the cardiovascular, endocrine and renal systems.
其他說明
Lyophilized from 0.1% TFA in H2O
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
James L Goodson et al.
Hormones and behavior, 50(2), 223-236 (2006-04-29)
Neuroendocrine factors that produce species differences in aggregation behavior ("sociality") are largely unknown, although relevant studies should yield important insights into mechanisms of affiliation and social evolution. We here focused on five species in the avian family Estrildidae that differ
Satoko Ise et al.
Brain research, 1234, 59-65 (2008-08-16)
An infant animal isolated from its mother emits vocalizations spanning from the audible to the ultrasonic. These vocalizations are believed to represent distress signals from the pup. However, the neurobiological basis for vocalizations elicited by isolation has not been well
David A Lovejoy et al.
General and comparative endocrinology, 146(1), 1-8 (2006-02-14)
The corticotropin-releasing factor (CRF) family of peptides consists of four distinct paralogs found on separate chromosomes in vertebrates. Among invertebrates, the family has been relatively well characterized in the insects where at least 2 or 3 paralogs, a CRF-binding protein
Donald R Gehlert et al.
The Journal of pharmacology and experimental therapeutics, 341(3), 672-680 (2012-03-10)
Corticotropin-releasing factor (CRF) is the major hypothalamic neuropeptide responsible for stimulation of the hypothalamic-pituitary-adrenal axis (HPAA), resulting in the synthesis and release of glucocorticoids from the adrenal cortex. In a recent study, we reported the discovery of the CRF1 receptor
Takeshi Nakamura et al.
American journal of physiology. Heart and circulatory physiology, 296(2), H325-H332 (2008-12-09)
Urocortin 3 (Ucn3) is a new member of the corticotropin-releasing factor (CRF) peptide family and is considered to be a specific and endogenous ligand for CRF type 2 receptors (CRF2Rs). The presence of CRF(2)Rs has been reported in the nucleus
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