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Merck

S3638

Sigma-Aldrich

Ser-Glu

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About This Item

经验公式(希尔记法):
C8H14N2O6
CAS号:
分子量:
234.21
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

儲存溫度

−20°C

SMILES 字串

NC(CO)C(=O)NC(CCC(O)=O)C(O)=O

InChI

1S/C8H14N2O6/c9-4(3-11)7(14)10-5(8(15)16)1-2-6(12)13/h4-5,11H,1-3,9H2,(H,10,14)(H,12,13)(H,15,16)

InChI 密鑰

LAFKUZYWNCHOHT-UHFFFAOYSA-N

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Laura Cipolla et al.
Future medicinal chemistry, 2(4), 587-599 (2011-03-24)
Several glycoprocessing enzymes and glycoreceptors have been recognized as important targets for therapeutic intervention. This concept has inspired the development of important classes of therapeutics, such as anti-influenza drugs inhibiting influenza virus neuraminidase, anti-inflammatory drugs targeting lectin-sialyl-Lewis X interaction and
T Tsukida et al.
Journal of medicinal chemistry, 41(22), 4279-4287 (1998-10-23)
We have previously found that heterochiral fucodipeptides, L-Ser-D-Glu (3a) and D-Ser-L-Glu (3b), exhibited up to 20-100 times more potency than a sialyl Lewis X (sLeX, 1) and a 3'-sulfated Lewis X analogue (2) toward E-selectin binding and have also proposed
T Tsukida et al.
Journal of medicinal chemistry, 40(22), 3534-3541 (1997-11-14)
We have rationally designed a sLe(x) mimetic based on molecular modeling, synthesized type II and type II' beta-turn dipeptides (3a,b), and evaluated their biological profiles both in vitro and in vivo. Against E-selectin-sLe(x) binding, the type II beta-turn dipeptide L-Ser-D-Glu

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